If you have an underactive thyroid gland. Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. If you forget to take a dose, take it as soon as you remember. This site complies with the HONcode standard for trustworthy health information: verify here. This is so your doctor can check on your progress. Isosorbide dinitrate (Isordil) is available as both a short-acting tablet and long-acting capsule. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). Learn to reduce stress through mindful living. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. Be sure to mention any of the following: aspirin; beta blockers such as atenolol (Tenormin, Tenoretic), carteolol , labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, in Dutoprol, in Lopressor HCT), nadolol (Corgard, in Corzide), propranolol (Hemangeol, Inderal, Innopran), sotalol (Betapace, Sorine, Sotylize), and timolol; calcium channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), diltiazem (Cardizem, Cartia, Dilt-CD, others), felodipine (Plendil), isradipine, nifedipine (Adalat CC, Afeditab, Procardia), and verapamil (Calan, Covera, Verelan); ergot-type medications such as bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Minimally clinically significant. Review/update the Let your provider know if you are using any medications for erectile dysfunction before you start taking isosorbide mononitrate (Monoket). Severe postural hypotension with light-headedness and dizziness is frequently observed after the consumption of alcohol. Contraindications: Isosorbide mononitrate should not be used in cases of acute myocardial infarction with low filling pressure, acute circulatory failure (shock, vascular collapse), or hypertrophic obstructive cardiomyopathy (HOCM), constrictive pericarditis, low cardiac filling pressures, aortic/mitral valve stenosis and diseases associated with a raised intra-cranial pressure e.g following a head trauma and including cerebral haemorrhage. Danshen. Making any changes without doctor's advice can be dangerous. Instead, the best way to dispose of your medication is through a medicine take-back program. Try to keep your regular appointments with your doctor. However, you should not flush this medication down the toilet. Accessed Sept. 7, 2022. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. Isosorbide mononitrate is also sometimes prescribed alongside other medicines for people with heart failure. Commonly reported side effects include: See also: isosorbide mononitrate side effects in more detail. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. This product is available in the following dosage forms: There is a problem with View more. Otherwise, call a poison control center right away. Available for Android and iOS devices. Am J Ther. Some conditions may become worse when the drug is suddenly stopped. What side effects can this medication cause? Clin Res Cardiol. Take the container with you, even if it is empty. URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Consult your pharmacist or local waste disposal company. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. We study millions of patients and 5,000 more each day. Isosorbide (C6H10O4), also called D-Isosorbide dinitrate, is a bio-product sourced from starch. https://naturalmedicines.therapeuticresearch.com. We study 23,548 Isosorbide mononitrate users. Drug interactions may change how your medications work or increase your risk for serious side effects. What You Need to Know, Angina (a specific type of chest pain) caused by heart disease. It does not work fast enough to relieve the pain of an angina attack that has already started. B12 and folic acid is essential along with iron. If you notice other effects not listed above, contact your doctor or pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. If you have any problems with the way your liver works, or any problems with the way your kidneys work. information and will only use or disclose that information as set forth in our notice of Mayo Clinic; 2021. May also be prescribed off label for Esophageal Spasm. Medicines Complete BNF 84th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. I took this for 4 days, and my headaches were unbearable. HHS Vulnerability Disclosure, Help Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. If we combine this information with your protected Isosorbide tablets are also used with other medications to treat heart failure. Your provider might temporarily have you stop isosorbide mononitrate (Monoket) if this happens. For details see our conditions. Canada residents can call a provincial poison control center. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. Take isosorbide exactly as directed. Normal ecg doesn't rule out heart disease. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. Does isosorbide mononitrate (Monoket) lower blood pressure? Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. Is not subject to the Controlled Substances Act. Dated August 2017. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). Pregnancy:Data on the use of isosorbide mononitrate during pregnancy are insufficient to be able to assess the possible harmful effect. The narrowing makes it more difficult for blood to flow to your heart muscle. Talk to your pharmacist for more details. Make sure laboratory personnel and all your doctors know you use this drug. If you notice any other effects, check with your healthcare professional. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. In: Current Medical Diagnosis & Treatment 2022. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. government site. Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed. The information on this page is written and peer reviewed by qualified clinicians. Never give it to other people even if their condition appears to be the same as yours. Browse Drugs and Medicines. Along with its needed effects, a medicine may cause some unwanted effects. Prescribed for Angina, Anal Fissure and Treatment and prognosis of heart failure with preserved ejection . The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. Real test is coronary angiography. Can isosorbide mononitrate cause problems? Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Registered in England and Wales. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). Take care, thanks. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. If you have an eye condition called glaucoma. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. It is important to take the drug at the same times each day. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Alternative cancer treatments: 11 options to consider. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. It is components of vit. Click here for an email preview. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. It has a very short duration of action and may not be suitable for some people. Duplication for commercial use must be authorized by ASHP. Prices for isosorbide mononitrate (Monoket) start at just $29.86 with a GoodRx coupon. You will find a full list in the manufacturer's information leaflet supplied with your medicine. What conditions does Isosorbide Mononitrate treat? This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). 19 are major, 174 are moderate, and 2 are minor. Valerian: A safe and effective herbal sleep aid? Some side effects may occur that usually do not need medical attention. Isosorbide mononitrate belongs to the group of medicines called nitrates. Get emergency help immediately if any of the following symptoms of overdose occur: bulging soft spot on the head of an infant, change in the ability to see colors, especially blue or yellow, feeling of constant movement of self or surroundings. If you have ever had an allergic reaction to a medicine. Your doctor may tell you to take a pain reliever to treat your headaches. Isosorbide mononitrate is a nitrate-class drug used for the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. ask your doctor about the safe use of alcoholic beverages while you are taking isosorbide. Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. Aspirin relieves pain and inflammation and helps to thin the blood. Isosorbide mononitrate should not be used in patients with severe anaemia, severe hypotension, closed angle glaucoma or severe hypovolaemia.Isosorbide mononitrate may give rise to postural hypotension and syncope in some patients. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Nitroglycerin has an average rating of Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. Methods: In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). Keep this medication in the container it came in, tightly closed, and out of reach of children. National Library of Medicine This content does not have an Arabic version. Anti-ischemic and anti-anginal effects of controlled-release and conventional isosorbide-5-mononitrate in stable angina pectoris. It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. Daily headaches are a common side effect. Who should not take Isosorbide Mononitrate? This drug may make you dizzy. Can cause dizziness, especially when you change positions, Interacts with erectile dysfunction medications. Accessed Sept. 7, 2022. What should I know about storage and disposal of this medication? It might help to take isosorbide mononitrate and dinitrate after meals. Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". It works by relaxing and widening blood vessels so blood can flow more easily to the heart.This medication will not relieve chest pain once it occurs. 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. Your body can get used to isosorbide mononitrate (Monoket), and the same amount of medication might no longer work as well as it used to. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or . Alcohol can make the side effects from isosorbide worse. The tablet usually is taken two or three times daily. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. All rights reserved. US residents can call their local poison control center at 1-800-222-1222. This survey is being conducted by the WebMD marketing sciences department. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. To use the sharing features on this page, please enable JavaScript. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Then, there was a two-week placebo washout, after which the alternative treatment was given. Therefore, oral nitrates should not be used by patients who are sensitive to the effects of hypotension, such as those with pre-existing hypotension, shock, vascular collapse or significant cerebrovascular disease, significant anaemia or hypothyroidism. Other medications may be prescribed by your doctor for these conditions. Patient does not provide medical advice, diagnosis or treatment. Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg. Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Some products have ingredients that could worsen your heart failure. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. Are you looking for information on isosorbide dinitrate (Isordil) instead? it is a safe and effective alternative; the choice between beta blockers and calcium channel blockers depends . This is called tolerance, and it cannot be fixed by raising the dose of the medication. These products are provided 'AS IS' and 'as available' for use, without warranties of any kind, either express or implied. Isosorbide mononitrate helps to prevent angina chest pain from developing. If tolerance is suspected during the use of transdermal patches they should be left off for 8-12 hours (usually overnight) in each 24 hours; in the case of modified-release tablets of isosorbide dinitrate (and . Longer-acting tablets and capsules are taken once daily in the morning. Glyceryl trinitrate (GTN) is commonly prescribed for this. May also be prescribed off label for Esophageal Spasm. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. The extended-release tablet usually is taken once daily in the morning. You can take your doses either before or after meals. The body tends to develop a tolerance (decreased sensitivity) to ISMN when it is used continuously over 24 hours. Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. Accessed Sept. 7, 2022. Please note that only the generic name of each medication is listed below. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. This medicine is available only with your doctor's prescription. eCollection 2021. Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. Upgrade to Patient Pro Medical Professional? Isosorbide mononitrate is used to prevent chest pain ( angina) in patients with a certain heart condition ( coronary artery disease ). Some products that may interact with this drug include: drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), riociguat. Danshen can interact strongly with some heart medicines, such as: Evening primrose may raise your risk of bleeding if you also take a blood thinner, such as: Garlic may raise your risk of bleeding if you also take a blood thinner, such as: Ginkgo biloba may raise your risk of bleeding if you also take a blood thinner, such as: If you take ginseng with warfarin, it may lessen how well warfarin works. May also be prescribed off label for Esophageal Spasm. Selected from data included with permission and copyrighted by First Databank, Inc. B complex. Please enable it to take advantage of the complete set of features! Vascular dilatation can precipitate venous pooling with decreased return to the heart, hypotension and reflex tachycardia. Isosorbide mononitrate is used to prevent chest pain in patients with a certain heart condition (coronary artery disease).This medication belongs to a class of drugs known as nitrates. The .gov means its official. Some of these medicine interactions can be risky. The use of the Truven Health products is at your sole risk. The herb licorice may lower warfarin levels and can add to digoxin's effects. Saw palmetto. Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. Use this medication regularly to get the most benefit from it. Ask your pharmacist for a list of the ingredients. If you suffer headaches when taking Isosorbide mononitrate, be patient. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Using this medicine with any of the following medicines is not recommended. DUMQOL (DUtch Mononitrate Quality of Life) Study Group. Limit alcoholic beverages. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. To view a report comparing 3 (or more) medications, please sign in or create an account. health information, we will treat all of that information as protected health Portions of this document last updated: Feb. 01, 2023. 72% of reviewers reported a positive effect, while 12% reported a negative effect. Isosorbide mononitrate (Monoket) is good for a specific type of chest pain (called angina), but it can cause headaches or dizziness after you take it. This side-effect usually disappears after a few days, Do not drive and do not use tools or machines while affected, If either of these becomes troublesome, speak with your doctor. It can cause your blood pressure to become dangerously low. Do not share this medication with others. Continue to take isosorbide even if you feel well. Do not change the dosing times unless directed by your doctor. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. and transmitted securely. Before When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Alcohol or marijuana (cannabis) can make you more dizzy. Usually avoid combinations; use it only under special circumstances. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. 8600 Rockville Pike If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. Evening primrose. About one-half of adults in the United States say they have used one or more supplements in the past 30 days. The effects of this exposure on a nursing infant are unknown. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. 2021 May 11;39:28. doi: 10.11604/pamj.2021.39.28.22180. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. The extended-release capsule usually is taken once daily. Garlic. Yet many herbal supplements may interact with heart disease medicines.
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